Figure 3. Human RPE cells form basal deposits rich in C5b-9_n (MAC) in vitro, and inhibitory effects of compstatin peptides. Representative cross-sectional images show 3-month-old RPE cell cultures labeled with anti-C5b-9_n (green) and 4',6-diamidino-2-phenylindole (DAPI; blue), following exposure to either 10% normal human serum (NHS) alone or together with Peptides 1 and 2 for 24 h. Cultures that received no NHS treatment served as negative control. Scale bar = 10 μm.