Figure 3. The effect of TTR on the migration of hRECs. A: The wound healing test for human retinal microvascular endothelial cells (hRECs) was performed in natural and diabetic retinopathy (DR) environments with TTR, and the relative wound density (RWD) was detected to reveal the migration efficiency. B: After the 36-h culture, in the natural environments (LG and LG+TTR), the RWD was slightly promoted by TTR (*: p = 0.002, F = 29.378). In LG+Hypoxia and LG+Hypoxia+TTR, the migration of hRECs was inhibited by TTR (#: p = 0.034, F = 7.476), and in HG and HG+Hypoxia, TTR significantly repressed the migration of hRECs (**:p < 0.001, F = 77.118 and ##: p = 0.005, F = 18.206). (n=3, mean±SD was calculated).