Figure 2. ALA protects retinal ganglion cells (RGCs) from ONC-induced damage. A, B, C, D: Quantitative analysis of RNA-binding protein with multiple splicing (Rbpms)-positive cells (mean ± standard error of the mean [SEM], n = 6 per group). A, B, C: Mean density was estimated in an area approximately the same distance from the optic disc (OD): 1 mm (A), 2 mm (B), and 3 mm (C) from the OD. D: The average number of Rbpms-positive cells/mm² was calculated. *** p<0.001 compared to control, ## p<0.01, ### p<0.001 compared to optic nerve crush (ONC) injury, + p<0.05, +++ p<0.001 compared to the alpha lipoic acid (ALA)-ONC group at the same time point.