Table 6 of
Ambreen, Mol Vis 2015; 21:985-999.
Table 6. Genotype and allele frequencies in control and AMD patients for IL-8 SNPs.
Genotype | t test | Control (N=100) | AMD (N=90) | Alleles | Allele frequency reported in Pakistan (%) [25] | Control | AMD | p value | ||
---|---|---|---|---|---|---|---|---|---|---|
p value | F value | p value | F value | HWE allele frequency | HWE allele frequency | |||||
rs4073 | ||||||||||
TT | 0.0001*** | 0.368 | 1.015 | 0.340 | 1.099 | T | 64 | 0.625 (62.5%) | 0.589 (58.9%) | 0.2366 |
AT | 0.007** | A | 36 | 0.375 (37.5%) | 0.411 (41.1%) | |||||
AA | 0.146 | |||||||||
rs2227306 | ||||||||||
CC | 0.0001*** | 0.125 | 2.148 | 0.951 | 0.050 | C | 74 | 0.73 (73%) | 0.84 (84%) | 0.0001*** |
CT | 0.0001*** | T | 26 | 0.27 (27%) | 0.16 (16%) | |||||
TT | 0.137 | |||||||||
rs2227543 | ||||||||||
CC | 0.0001*** | 0.710 | 0.495 | 0.002** | 6.80 | C | 68 | 0.66 (66%) | 0.555 (55.5%) | 0.0372 |
CT | 0.0001*** | T | 32 | 0.34 (34%) | 0.445 (45.5%) | |||||
TT | 0.833 |