Table 5 of
Ambreen, Mol Vis 2015; 21:985-999. Table 5 of
Ambreen, Mol Vis 2015; 21:985-999.
Table 5. Genotype and allele frequencies in control and AMD patients for IL-6 SNPs.
| Genotype | t test | Control (N=100) | AMD (N=90) | Alleles | Allele frequency reported in Pakistan (%) [25] | Control | AMD | p value | ||
|---|---|---|---|---|---|---|---|---|---|---|
| p value | F value | p value | F value | HWE allele frequency | HWE allele frequency | |||||
| rs1800795 | ||||||||||
| GG | 0.0001*** | 0.105 | 2.707 | 0.0001*** | 8.801 | G | 87 | 0.865 (86.5%) | 0.633 (63.3%) | 0.0001*** |
| GC | 0.916 | C | 13 | 0.135 (13.5%) | 0.367 (36.7%) | |||||
| CC | NA | |||||||||
| rs1800796 | ||||||||||
| GG | 0.010* | 0.514 | 0.671 | 0.293 | 1.254 | G | 67 | 0.59 (59%) | 0.583 (58.3%) | 0.896 |
| GC | 0.0001*** | C | 33 | 0.41 (41%) | 0.417 (41.7%) | |||||
| CC | 0.044* | |||||||||
| rs1800797 | ||||||||||
| GG | 0.0001*** | 3.154 | 0.081 | 0.254 | 0.616 | G | 86 | 0.82 (82%) | 0.96 (96%) | 0.0001*** |
| GA | 0.733 | A | 14 | 0.18 (18%) | 0.04 (4%) | |||||
| AA | NA | |||||||||