Figure 2. Increased ZEB1, Twist1, and Snail1 mRNA levels in invasive uveal melanoma cells. The mRNA levels of the EMT-factors ZEB1, Twist1, and Snail1 were significantly increased, as measured by qPCR, in invading OMM1 cells, which moved through a Matrigel-coated filter, as compared to non-invading OMM1 cells. Data shown are mean ± standard deviation (SD); *p = 0.028; **p = 0.002; ***p = 0.0005 versus non-invading cells.