Figure 1. Autofluorescence (AF) images, color photographs, red-free photographs, and OCT examinations of subjects 5, 7, and 8. In subject
5, (A–C), the AF (A) image shows a hyperfluorescent spot in the left macula corresponding with pigmentary changes on fundus photos (B and C). In subject 7 (D–H), the AF image (D) shows discrete hyper- and hypofluorescence around the vascular arcades. E and F show subtle pigmentary changes in the macula and along the vascular arcades, seen most clearly in the red-free photo (F). The OCT B-scan (G) shows subtle outer retinal disruption, but the retinal thickness (H) is within normal limits. The AF image (I) from subject 8 demonstrates multiple foci with mixed hyper- and hypofluorescence. Fundus photographs (J and K) also reveal widespread orange-yellow flecks in the posterior pole, as well as macular pigmentary changes. The OCT B-scan
(L) shows outer retinal disruption, although the retinal thickness (M) is within normal limits.