Figure 2 of Russo, Mol Vis 2015; 21:718-729.

Figure 2. Intravitreal application of homotaurine and L-carnosine potentiates the neuroprotection afforded by forskolin in retinas subjected to ischemia/reperfusion. Intravitreal treatment with homotaurine (0.059 μmol/eye) and L-carnosine (0.036 μmol/eye) did not afford neuroprotection following retinal ischemia; administration of the two compounds in combination with forskolin (100 μM) significantly potentiated the survival of retinal ganglion cells (RGCs; evaluated 7 days following retinal ischemia) compared to forskolin alone. A: Representative photomicrographs of FluoroGold (FG)-labeled RGCs in whole-mount retinas are shown. Scale bar=75 μm. B: Histogram shows the results of the FG-labeled RGC count expressed as mean ± SEM of four independent experiments (**p<0.01, ***p<0.001 versus vehicle-treated ischemic retinas; #p<0.05; ANOVA followed by Tukey-Kramer multiple comparisons test). (FSK: forskolin; Hom: homotaurine; Carn: L-carnosine; C: control non-ischemic retina; I/R: ischemic retina).