Figure 4. Mechanism of unoprostone isopropyl-mediated vasodilation.Co-incubation with NG-nitro-L-arginine methyl ester (L-NAME; 10 µM)
and iberiotoxin (0.1 µM, n = 4) almost eliminated the retinal arteriolar dilation in response to unoprostone isopropyl. *p<0.05
versus control.