Figure 1. Inhibitory effect of fasudil eye drops on corneal neovascularization (CNV). A: Representative images of the murine corneas after alkali burns with and without fasudil eye drops. B: The percentages of CNV in the fasudil and phosphate-buffered saline (PBS) groups at every checkpoint. The percentages of CNV in the 30, 100, 300, and 1000 μM fasudil groups were 40.29%±6.30%, 32.54%±3.76%, 38.49%±6.27%, and 41.67%±8.78% on day 4; 48.61%±9.65%, 40.40%±8.15%, 46.36%±10.81%, and 49.52%±11.65% on day 7; 78.28%±10.21%, 54.17%±10.71%, 63.23%±14.32%, and 78.00%±11.57% on day 10; 95.89%±3.23%, 67.45%±15.45%, 82.38%±12.43%, and 93.16%±3.70% on day 14. The percentages of CNV in the PBS group were 39.04%±8.07%, 52.24%±10.58%, 79.34%±12.96%, 96.07%±3.32% on day 4, 7, 10, and 14, respectively (n=15/group, * indicates p<0.05, ** indicates p<0.01).