Table 2 of
Brzović-Šarić, Mol Vis 2015; 21:649-664. Table 2 of
Brzović-Šarić, Mol Vis 2015; 21:649-664.
Table 2. Mean values of measured parameters by age groups and the correlation analysis of measured parameters with age in non-diabetic patients with eye disorders (NDED) and proliferative diabetic retinopathy (PDR) patients.
| Mean by age groups (years) ± S.E | Spearman correlation (ρ) | ||||||
|---|---|---|---|---|---|---|---|
| Parameter | Group | ≤60 | 61-65 | 66-70 | 71-75 | ≥76 | |
| VEGF (pg/l) | NDED | 86.8 ± 10.8 | 217.1 ± 99.3 | 224.3 ± 104.5 | 238.0 ± 56.1 | 139.5 ± 41.5 | 0.224 |
| PDR | 1594.3 ± 473.7* | 2274.1 ± 804.0* | 2268.0 ± 843.9* | 1401.6 ± 222.7* | 1158.7 ± 514.4* | -0.032 | |
| AOPP (µM) | NDED | 29.0 ± 16.5 | 62.6 ± 54.6 | 56.2 ± 46.6 | 39.1 ± 12.6 | 44.0 ± 13.9 | -0.242 |
| PDR | 66.5 ± 22.3 | 33.4 ± 10.6 | 53.2 ± 32.6 | 81.0 ± 46.5 | 143.0 ± 104.3 | 0.022 | |
| LPO (µM) | NDED | 26 .0 ± 3.5 | 33.8 ± 6.1 | 34.8 ± 4.9 | 25.0 ± 4.1 | 27.4 ± 4.8 | -0.195 |
| PDR | 153.3 ± 9.7* | 139.2 ± 7.5* | 117.0 ± 14.1* | 151.0 ± 18.9* | 147.0 ± 18.8* | -0.178 | |
| MDA (nmol/ml) | NDED | 33.0 ± 10.1 | 60.9 ± 22.2 | 99.8 ± 43.1 | 46.5 ± 12.3 | 61.3 ± 14.5 | 0.072 |
| PDR | 91.7 ± 5.5* | 103.5 ± 4.7 | 48.4 ± 11* | 57.5 ± 42.6 | 123.2 ± 39.5* | -0.011 | |
| SOD (U/ml) | NDED | 48.3 ± 3.4 | 47.5 ± 18.9 | 90.3 ± 32.1 | 72.2 ± 18.1 | 72.5 ± 14.7 | 0.307 |
| PDR | 25.6 ± 3.5* | 37.3 ± 3.7 | 24.8 ± 5.8* | 29.0 ± 8.3* | 30.0 ± 2.1* | 0.100 | |
| GSH (µmol/ml) | NDED | 36.6 ± 7.6 | 44.2 ± 5.0 | 41.5 ± 2.5 | 38.5 ± 0.3 | 39.1 ± 0.3 | -0.098 |
| PDR | 43.6 ± 3.1 | 43.3 ± 2.7 | 50.7 ± 7.9 | 52.0 ± 11.8 | 41.2 ± 0.8 | 0.070 | |
| Serum | Spearman correlation (ρ) | ||||||
| ≤60 | 61-65 | 66-70 | 71-75 | ≥76 | |||
| VEGF (pg/l) | NDED | 15.3 ± 4.3 | 27.7 ± 8.7 | 21.0 ± 6.3 | 17.2 ± 3.9 | 25.8 ± 6.6 | -0.136 |
| PDR | 34.2 ± 6.6* | 61.3 ± 20.2 | 175.1 ± 146.3 | 36.6 ± 4.4* | 72.4 ± 21.8* | 0.407# | |
| AOPP (µM) | NDED | 238.0 ± 42.6 | 283.0 ± 35.3 | 198.1 ± 44.2 | 241.1 ± 25.0 | 240.8 ± 24.9 | -0.176 |
| PDR | 451.2 ± 77.1* | 501.4 ± 109.8* | 438.2 ± 108.0* | 235.6 ± 79.7 | 275.0 ± 94.0 | -0.236 | |
| LPO (µM) | NDED | 21.0 ± 3.8 | 23.4 ± 2.6 | 19.0 ± 3.7 | 26.8 ± 2.5 | 30.4 ± 3.5 | 0.289 |
| PDR | 177.6 ± 7.6* | 162.4 ± 7.3* | 147.0 ± 24.2* | 176.0 ± 15.7* | 150.2 ± 25.6* | -0.260 | |
| MDA (nmol/ml) | NDED | 27.4 ± 4.4 | 32.9 ± 6.7 | 29.5 ± 8.4 | 30.1 ± 7.4 | 31.6 ± 6.4 | -0.156 |
| PDR | 171.1 ± 12.1* | 165.9 ± 33.5* | 132.2 ± 11.9* | 128.6 ± 16.0* | 107.4 ± 3* | -0.427# | |
| SOD (U/ml) | NDED | 28.4 ± 4.0 | 22.2 ± 2.1 | 22.0 ± 2.9 | 23.6 ± 2.1 | 27.1 ± 2.0 | 0.179 |
| PDR | 208.5 ± 43.6* | 122.1 ± 14.01* | 95.3 ± 11.9* | 107.2 ± 45.6* | 126.8 ± 12.2* | -0.443# | |
| GSH (µmol/ml) | NDED | 73.0 ± 8.0 | 101.9 ± 21.7 | 92.8 ± 13.0 | 89.7 ± 8.4 | 80.5 ± 6.8 | -0.111 |
| PDR | 70.9 ± 4.8 | 74.6 ± 4.3 | 85.1 ± 1.7 | 60.0 ± 14.9 | 70.7 ± 3.9 | -0.062 | |