Figure 2. Expression of LGR5 in inflamed human limbal stem cell niches. Leucine-rich repeat-containing G protein-coupled receptor 5 (LGR5) was variously expressed in limbal epithelial crypts (LECs; arrows). A: Three out of five samples were negative. B: In two cases, we observed a moderate grade of positivity. No correlation was found with the number of inflammatory cells (arrowheads). Each section was counterstained with hematoxylin. Bar scale=50 micron. Magnification X200. * Indicates the limbal side of the specimen.