Figure 1. LGR5 immunohistochemical staining in the human healthy stem cell niche and in the cornea. A: The expression of leucine-rich repeat-containing G protein-coupled receptor 5 (LGR5) was localized in the cytoplasm of limbal cell niche. B: No positivity was observed with specific isotype control. C: LGR5 was not detected in the cornea. Each section was counterstained with hematoxylin. Bar scale=50 micron. Magnification X200. * Indicates the limbal side of the specimen.