Figure 4. Effect of blockade of IL-4 on frequency of CD4+CD30+ T cells after D. pteronyssinus (Der p) stimulation. Peripheral blood mononuclear cells (PBMCs) from three patients with vernal keratoconjunctivitis (VKC) were
stimulated with Dermatophagoides pteronyssinus for 7 days, and mAb anti-interleukin-4 (IL-4) was added at baseline, 3 d, and 5 d as described in the Materials and Methods
section. The plot shows the significant diminished frequency of CD4+CD30+ T cells when IL-4 was blocked.