Figure 3. Soluble CD30 is secreted early after Concanavalin A (Con A) stimulation. Peripheral blood mononuclear cells (PBMCs) were stimulated at 24, 48, 72, and 96 h, and the supernatant of the cultures was collected to determine soluble CD30. An increased significant concentration of soluble CD30 was observed at 72 and 96 h after Con A stimulation. Results are representative of eight patients with vernal keratoconjunctivitis (VKC) and matched controls.