Table 2 of
Wu, Mol Vis 2015; 21:412-416. Table 2 of
Wu, Mol Vis 2015; 21:412-416.
Table 2. KLC1, PSEN1 and APOE genotype and allele distribution.
| SNP | Genotype (%) | HWE | P value | Allele frequency (%) | P value | OR (95%CI) | |||
|---|---|---|---|---|---|---|---|---|---|
| rs8702 | GG | CG | CC | 0.008 | G | C | 0.001 | 1.54 (1.19 −2.01) | |
| Cases (n=227) | 111 (0.49) | 90 (0.40) | 26 (0.11) | 0.24 | 312 (0.69) | 142 (0.31) | |||
| Controls(n=263) | 95 (0.36) | 119 (0.45) | 49 (0.19) | 0.28 | 309 (0.59) | 217 (0.41) | |||
| rs165932 | AA | AT | TT | 0.53 | A | T | 0.28 | 0.85 (1.62 −1.14) | |
| Cases (n=227) | 128 (0.56) | 85 (0.38) | 14 (0.06) | 0.98 | 341 (0.75) | 113 (0.25) | |||
| Controls(n=263) | 135 (0.51) | 109 (0.42) | 19 (0.07) | 0.64 | 379 (0.72) | 147 (0.28) | |||
| rs7523 | GG | GA | AA | 0.54 | G | A | 0.40 | 1.16 (0.82 −1.63) | |
| Cases (n=227) | 158 (0.70) | 60 (0.26) | 9 (0.04) | 0.28 | 376 (0.83) | 78 (0.17) | |||
| Controls (n=263) | 189 (0.72) | 68 (0.24) | 6 (0.02) | 0.97 | 446 (0.85) | 80 (0.15) | |||
| APOE | E3/E3 | E3/E4 | E4/E4 | 0.11 | E3 | E4 | 0.03 | 1.74 (1.05 – 2.90) | |
| Cases (n=227) | 191 (0.84) | 33 (0.15) | 3 (0.01) | 0.26 | 415 (0.91) | 39 (0.09) | |||
| Controls (n=263) | 238 (0.90) | 23 (0.09) | 2 (0.01) | 0.10 | 501 (0.95) | 27 (0.05) | |||