Figure 3. DIZE downregulated mRNA expressions of inflammatory cytokines and NF-κB p65 in EIU rats. The iris ciliary body complexes were used to detect the mRNA of inflammatory cytokines, including IL-1β, TNF-α, COX-2, iNOS, and NF-κB p65. 0.1% DIZE eyedrops inhibited the mRNA expressions of IL-1β (A), TNF-α (B), COX-2 (C), iNOS (D), and NF-κB p65 (E) in EIU rats 24 h after LPS injection. Values represented mean±SD (n=4). *p<0.05, **p<0.01, ***p<0.001.