Table 1 of
Chi, Mol Vis 2015; 21:335-346. Table 1 of
Chi, Mol Vis 2015; 21:335-346.
Table 1. Main characteristics and methodological quality of all eligible studies.
| First author | Year | Country | Disease | Number | Gender (M/F) | Age (year) | Genotyping method | Gene | SNP | NOS score | |||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Case | Control | Case | Control | Case | Control | ||||||||
| Xu HF [38] | 2013 | China | Senile cataract | 260 | 269 | - | - | 67.0±10.6 | 68.8±10.5 | Direct sequencing | XPD | Lys751Gln A>C | 6 |
| Guo MJ [34] | 2013 | China | Senile cataract | 260 | 276 | - | - | 67.0±11.0 | 68.8±10.5 | Direct sequencing | XRCC1 | Arg399Gln G>A | 6 |
| Zhang Y [24] | 2012 | China | Cortical | 415 | 386 | 220/195 | 202/184 | 67.17±6.9 | 65.8±6.5 | PCR-RFLP | XRCC1 | Arg399Gln G>A | 8 |
| Padma G [12] | 2011 | India | Senile cataract | 208 | 151 | 91/117 | 94/57 | 58.6±0.4 | 49.1±0.6 | PCR-RFLP | XRCC1 | Arg399Gln G>A | 8 |
| Luo YF [33] | 2011 | China | Senile cataract | 180 | 174 | 65/115 | 61/113 | 68.0±8.0 | 61.5±7.0 | PCR-RFLP | XPD | Lys751Gln A>C | 7 |
| Senile cataract | XRCC1 | Arg399Gln G>A | |||||||||||
| Unal M [25] | 2007 | Turkey | Cortical / Cortical / Posterior subcapsular /Mixed | 195 | 194 | 99/96 | 105/89 | 64.0±8.0 | 63.0±8.0 | PCR-RFLP | XPD | Lys751Gln A>C | 8 |
| Cortical / Cortical / Posterior subcapsular /Mixed | XRCC1 | Arg399Gln G>A | |||||||||||