Table 1 of Grybauskas, Mol Vis 2015; 21:201-212.

Table 1. Gene expression of human ABC transporters in ocular tissues.

Gene Alias Probeset Trabecular meshwork Ciliary body Optic nerve Optic nerve head
ABCB1 P-glycoprotein/MDR1 3,060,182 33.27 23.14 30.13 45.95
ABCC1 MRAP-1 3,649,890 28.76 26.45 26.75 24.73
CYP3A5 Cytochrome P450 3A5 3,063,406 31.92 32.63 28.74 37.14

Level of expression of ABC transporters was determined from the Ocular Tissue Database, a collection of data using Affymetrix Human Exon 1.0 ST arrays. Probe Logarithmic Intensity ERror (PLIER) values were used to determine significance of expression for ABCB1 and ABCC1 transporters. *Remaining 46 human ABC transporters were determined to have notable expression using a threshold ≥30 PLIER value.

Grybauskas, Mol Vis 2015; 21:201-212. http://www.molvis.org/molvis/v21/201

©2015 Molecular Vision http://www.molvis.org/molvis/

ISSN 1090-0535