Figure 7. Effect of R667 on IOP in rats after glaucoma filtration surgery. A: Representative photograph of the left eye at 14 days after surgery. B: Intraocular pressure (IOP) of the left eye at the indicated times after filtration surgery for rats treated with R667 or vehicle (PBS) during the procedure. Data are means ± standard deviation (SD) for five animals in each group. *p<0.05 versus the corresponding preoperative (time 0) value (Holm’s pairwise t test); †p<0.05 versus the corresponding value for rats treated with PBS (the Mann–Whitney U test).