Figure 1. Effects of CDECM on tear production. Changes in the tear volumes of the experimental PBS- and chondrocyte-derived extracellular
matrix (CDECM)-instilled NOD.B10.H2b mice after the elimination of desiccation stress (DS). PBS or CDECM was instilled five times per day for the indicated number
of days, and the tear volumes of the NOD.B10.H2b mice were measured after 3, 5, 7, and 10 days of instillation. The quantitative data are presented as mean ± standard deviation
(SD). *p<0.05 versus the value in the PBS group. #p<0.05 versus the corresponding value in the DS 10 day (10D) group.