ARPE-19 cells were stimulated with poly(I:C) (1 μg/ml) in the absence or presence of C5a (50 ng/ml) for 16h. C5a was added to the culture 10 min prior to poly(I:C) challenge. Effect of C5a on TLR3-indcuced IL-6 (A) and IL-8 (B) mRNA expression in ARPE-19 cells. The data are expressed as mean±SEM of three independent experiments. Statistical analysis was performed using one-way ANOVA. (* indicates p < 0.05 and ** indicates p < 0.01). To access these data, click or select the words "Appendix 2".