Figure 4. Effects of MYOC Mutations on NF-kappaB Activity in Stably Transduced Cell Lines TBM-1 cell lines stably transduced with wild-type or mutant MYOC lentivirus expression constructs were transfected with the IL8-luc expression construct or the renilla expression construct control. MYOC expression was then induced in at 1000 ng/ml doxycycline. A set of cultures was treated with IL1A and a parallel was left untreated for comparison. *p<0.05 n=3.