Some T cell clones obtained from the cerebrospinal fluid of the Vogt-Konayagi-Harada (VKH) patient secrete interleukin (IL)-17.
T cell clones (n≥107) were stimulated with beads coated with anti-CD3 and anti-CD28 antibodies. The amount of IL-17 in the
supernatant of overnight co-cultures was measured by multiplex bead-based assay. The horizontal lines represent the mean ±
SEM. None of the clones shown in Figure 6
and Figure 7
secreted significant amounts of IL-17.