Figure 3. Compound 49b treatment reduces suppressor of cytokine signaling 3 and insulin receptor^Tyr960 in β2-adrenergic receptor knockout mice. A: Suppressor of cytokine signaling 3 (SOCS3) levels in control, β2-adrenergic receptor knockout mice+49b, and β2-adrenergic receptor knockout (KO) mice are shown. B: Phosphorylation of tyrosine 960 on the insulin receptor in the same animal groups. *p<0.05 versus wild-type (WT); #p<0.05 versus β2-adrenergic receptor KO mice. n = 5 for all groups. Data are mean ± standard error of the mean (SEM).