Figure 6. Effect of Cx43 downregulation on retinal thickness. Representative optical coherence tomography scans indicate increased retinal
thickness in the diabetic rats and those injected with Cx43 siRNA compared to the non-diabetic or scrambled siRNA-injected
control rats. Retinal thickness assessment around the midretina was made from the (A) non-diabetic control rats, (B) diabetic rats, (C) non-diabetic rats intravitreally injected with Cx43 siRNA, and (D) non-diabetic rats intravitreally injected with scrambled siRNA. Graphical illustration of cumulative data indicates significant
overall thickening in the retinas of the diabetic rats and the rats injected with Cx43 siRNA compared to those of the control
rats. Data are presented as mean ± SD (*p<0.05, n=4).