Table 4 of
Mimiwati, Mol Vis 2014; 20:714-723. Table 4 of
Mimiwati, Mol Vis 2014; 20:714-723.
Table 4. Association between clinical parameters in JOAG probands and genotype frequency of Asn 480 Lys and IVS 2 730+35G>A (rs2032555).
| Genotype | ||||||||
|---|---|---|---|---|---|---|---|---|
| Clinical parameter | Asn 480 Lys | p-value | IVS 2 730+35G>A | p-value | ||||
| CC n=2 | CA n=25 | AA n=5 | CC n=5 | CA n=22 | AA n=5 | |||
| Mean age (SD; year) n=32 | 40.0 (9.9) | 29.5 (9.1) | 24.4 (8.8) | 0.457* | 26.0 (6.9) | 29.5 (9.1) | 28.6 (10.2) | 0.742* |
| n=2 | n=17 | n=3 | n=3 | n=17 | n=2 | |||
| Mean IOP (SD) (mmHg) n=22 | 34.5 (16.2) | 40.4 (12.8) | 27.0 (6.6) | 0.284* | 42.0 (16.5) | 36.6 (12.9) | 44.0 (22.6) | 0.681* |
| Mean VCDR | 0.56 (0.25) | 0.70 (0.24) | 0.58 (0.22) | 0.280* | 0.62 (0.27) | 0.69 (0.22) | 0.59 (0.28) | 0.557* |
| Visual field defect | n=2 | n=17 | n=4 | n=5 | n=17 | n=1 | ||
| Mean MD (SD) n=23 | −23.64 (2.07) | −10.21 (12.11) | −5.28 (6.33) | 0.184* | −9.86 (11.53) | −11.20 (12.03) | −2.27 (-) | 0.763* |
| n=2 | n=19 | n=4 | ||||||
| Mean CCT (SD; µm) n=25 | 523 (11) | 518 (34) | 511 (41) | 0.890* | 510 (16) | 518 (38) | 524 (20) | 0.834* |
| Severity | ||||||||
| Early | 0 | 9 | 3 | 0.738# | 3 | 8 | 1 | 0.839# |
| Mild | 0 | 2 | 0 | 0 | 2 | 0 | ||
| Moderate | 0 | 1 | 0 | 0 | 1 | 0 | ||
| Severe | 2 | 13 | 2 | 2 | 11 | 4 | ||