Table 3 of
Singh, Mol Vis 2014; 20:704-713. Table 3 of
Singh, Mol Vis 2014; 20:704-713.
Table 3. Observed genotype frequencies for studied SNPs among T2DM cases.
| SNP and genotype | Controls, no., (%) | T2DM, no., (%) | OR | 95% CI | p- value |
|---|---|---|---|---|---|
| rs4986790 (TLR4_Asp299Gly) 119515123 | |||||
| AA | 247 (77.2) | 287 (76.0) | – | – | – |
| AG | 73 (22.8) | 89 (23.5) | 1.01 | 0.71 to 1.44 | 0.93 |
| GG | 0 (0) | 2 (0.5) | 6.2 | 0.38 to 101.4 | 0.19 |
| AG + GG | 73 (22.8) | 91 (24.1) | 1.01 | 0.71 to 1.44 | 0.84 |
| rs4986791 (TLR4_Thr399Ile) 119515423 | |||||
| CC | 262 (81.9) | 302 (79.9) | – | – | – |
| CT | 54 (16.9) | 73 (19.3) | 1.17 | 0.79 to 1.72 | 0.42 |
| TT | 4 (1.2) | 3 (0.8) | 0.65 | 0.14 to 2.89 | 0.57 |
| CT + TT | 58 (18.1) | 76 (20.1) | 1.13 | 0.77 to 1.65 | 0.35 |
| rs10759931 (TLR4_1859) 120464147 | |||||
| AA | 173 (54.1) | 183 (48.4) | – | – | – |
| AG | 144 (45.0) | 194 (51.3) | 1.26 | 0.93 to 1.70 | 0.12 |
| GG | 3 (0.9) | 1 (0.3) | 0.34 | 0.04 to 2.48 | 0.29 |
| AG + GG | 147 (46.0) | 195 (51.6) | 1.25 | 0.92 to 1.67 | 0.14 |
| rs1927914 (TLR4_2437) 120464725 | |||||
| TT | 184 (57.5) | 181 (47.9) | – | – | – |
| TC | 134 (41.9) | 181 (47.9) | 1.37 | 1.01 to 1.85 | 0.04 |
| CC | 2 (0.6) | 16 (4.2) | 4.8 | 1.86 to 12.36 | 0.001 |
| TC + CC | 136 (42.5) | 197 (52.1) | 1.46 | 1.09 to 1.97 | 0.001 |
| rs1927911 (TLR4_7764) 120470054 | |||||
| CC | 112 (35.0) | 177 (46.8) | – | – | – |
| CT | 164 (51.2) | 169 (44.7) | 0.65 | 0.47 to 0.89 | 0.008 |
| TT | 44 (13.8) | 32 (8.5) | 0.45 | 0.27 to 0.76 | 0.002 |
| CT + TT | 212 (66.3) | 201 (53.2) | 0.6 | 0.44 to 0.81 | 0.001 |