Figure 4. Dynamic response of malignant melanoma and ARPE-19 cell exposure to vascular endothelial growth factor (VEGF). A and B represent the dynamic response of malignant melanoma cells with different concentrations of VEGF, as follows: untreated malignant melanoma cells (control, 0 ng/ml); l ng/ml VEGF; 5 ng/ml VEGF, 10 ng/ml VEGF; and 20 ng/ml VEGF. B: Comparison of increases in cell activity in the presence of VEGF after malignant melanoma cells were incubated in the cell system for about 72 h. *p<0.05 compared to untreated cells. C and D show the dynamic response of ARPE-19 with different concentrations of VEGF, as follows: untreated cells (control); l ng/ml VEGF; 5 ng/ml VEGF, 10 ng/ml VEGF, and 20 ng/ml VEGF. D: Comparison of increases in cell activity in the presence of VEGF after ARPE-19 were incubated in the cell system for about 72 h. *p<0.05 compared to untreated cells. Data represents three independent experiment and all data points plotted as mean values±SD (*p<0.05).