Figure 1 of Li, Mol Vis 2014; 20:649-660.

Figure 1. An overview, hematoxylin and eosin (H&E) staining, and immunohistochemical staining of malignant melanoma. A: An overview of the tumor. B: H&E staining of the tissue of malignant melanoma. C: H&E staining depigmented by KMnO4 (potassium permanganate) of malignant melanoma. The tissue was constituted by fusiform and epithelioid malignant melanoma cells. Cytoplasm was abundant with melanin granules. Nuclei was big with prominent nucleoli. D: Expression of HMB-45 in immunohistochemical staining of malignant melanoma was positive. E: Expression of Melan-A was weakly positive; F: Expression of S-100 protein was positive. G: Negative control. DAB was used as chromogen. (magnification: 200×).