Table 5 of Querques, Mol Vis 2014; 20:575-592.


Table 5. Changes in mean measurements and in specific features in patients with Best vitelliform macular dystrophy reverting or not from vitelliruptive stage to pseudohypopyon stage.

Vitelliruptive to pseudohypopyon (n=3)FU: 53.0±25.5 months Study entry Last visit P value
BCVA (LogMAR) 0.2±0.1 0.2±0.1 -
Overall lesion area (mm2) 4.57±2.7 5.36±3.0 0.1
Hyperautofluorescent component of the lesion (mm2) 0 1.87±1.5 0.01
Hypoautofluorescent component of the lesion (mm2) 4.57±2.7 3.49±1.3 0.03
FAF fovea (n) Hypo=3 Hypo=3 -
EZ status fovea (n) Disrupted=3 Disrupted=3  
OCT reflectivity (n) Hypo=3 Mixed=3 -
Maximal OCT lesion thickness (μm) 285.2±44.2 291.5±51.6 0.1
Maximal OCT lesion width (μm) 2289.2±382.1 2329.5±457.5 0.3
OCT neurosensory retinal thickness fovea (μm) 92.4±4.3 89.0±5.6 0.1
CMT (μm) 397.2±61.4 417.0±52.3 0.1
Vitelliruptive not progressing to pseudohypopyon (n=5)FU: 52.8±4.6months Study entry Last visit P value
BCVA (LogMAR) 0.28±0.2 0.26±0.2 -
Overall lesion area (mm2) 5.15±4.0 5.5±4.0 0.1
Hyperautofluorescent component of the lesion (mm2) 0 0 -
Hypoautofluorescent component of the lesion (mm2) 5.15±4.0 5.5±4.0 0.1
FAF fovea (n) Hypo=5 Hypo=5 -
EZ status fovea (n) Disrupted=5 Disrupted=5  
OCT reflectivity (n) Mixed=5 Mixed=5 -
Maximal OCT lesion thickness (μm) 233.6±99.6 188.8±120.4 0.02
Maximal OCT lesion width (μm) 2283.0±822.6 1818.8±592.0 0.07
OCT neurosensory retinal thickness fovea (μm) 105.2±50.9 81.2±19.4 0.04
CMT (μm) 361.4±52.2 365.6±33.9 0.8