Table 4 of Querques, Mol Vis 2014; 20:575-592.


Table 4. Changes in mean measurements and in specific features in patients with Best vitelliform macular dystrophy progressing or not from pseudohypopyon stage to vitelliruptive stage.

Pseudohypopyon to vitelliruptive (n=3)FU: 32.3±25.5 months Study entry Last visit P value
BCVA (LogMAR) 0.36±0.5 0.36±0.5 -
Overall lesion area (mm2) 5.32±2.9 5.16±3.3 0.6
Hyperautofluorescent component of the lesion (mm2) 2.41±1.8 0 0.01
Hypoautofluorescent component of the lesion (mm2) 2.91±2.7 5.16±3.3 0.01
FAF fovea (n) Hypo=3 Hypo=3  
EZ status fovea (n) Disrupted=2/ Normal=1 Disrupted=3  
OCT reflectivity (n) Mixed=3 Hypo=3  
Maximal OCT lesion thickness (μm) 226.5±13.2 215.6±15.4 0.1
Maximal OCT lesion width (μm) 2110.5±895.9 2056.0±648.4 0.3
OCT neurosensory retinal thickness fovea (μm) 92.5±16.4 90.7 14.5 0.1
CMT (μm) 332.0±13.7 323.0±21.1 0.1
Pseudohypopyon not progressing to vitelliruptive (n=3)FU: 45.3±28.9 months Study entry Last visit P value
BCVA (LogMAR) 0.22±0.11 0.26±0.1 0.1
Overall lesion area (mm2) 6.93±3.8 7.24±4.6 0.6
Hyperautofluorescent component of the lesion (mm2) 3.19±1.2 2.64±1.6 0.07
Hypoautofluorescent component of the lesion (mm2) 3.74±1.8 4.60±1.5 0.07
FAF fovea (n) Hypo=3 Hypo=3 -
EZ status fovea (n) Disrupted=2/ Normal=1 Disrupted=3  
OCT reflectivity (n) Mixed=3 Mixed=3 -
Maximal OCT lesion thickness (μm) 321.4±71.8 293.5±88.4 0.2
Maximal OCT lesion width (μm) 2925.4±320.6 2815.0±331.8 0.1
OCT neurosensory retinal thickness fovea (μm) 94.6±15.3 87.5±14.8 0.1
CMT (μm) 450.4±41.4 423.0±60.8 0.1