Figure 3. Patient #2. Blue fundus autofluorescence (FAF) and spectral-domain optical coherence tomography (SD-OCT) reveal the right eye affected with vitelliform lesion at both study entry and last follow-up visit (61 months later). Blue FAF frames show a highly autofluorescent macular lesion at study entry (top left panel, arrowhead), which was enlarged at the last follow-up visit (bottom left panel, arrowhead). SD-OCT scans show a hyperreflective dome-shaped lesion located in the subretinal space, between the hyperreflective photoreceptor inner segment (IS) ellipsoid portion (ellipsoid zone, EZ) and the hyperreflective retinal pigment epithelium (RPE)/Bruch’s membrane complex at study entry (top right panel), which had increased at the last follow-up visit (bottom right panel).