Table 3 of He, Mol Vis 2014; 20:545-552.

Table 3. Clinical profile of retinoblastoma probands (staging).

Groups total no. of eyes staging (no. and %)
A B C D E Extraocular
null mutation 61 3 (4.9%) 8 (13.1%) 16 (26.2%) 10 (26.4%) 20 (32.8%) 4 (6.6%)
in-frame mutation 15 1 (6.7%) 1 (6.7%) 0 4 (26.7%) 8 (53.3%) 1 (6.7%)
negative genetic testing results 48 1 (2.1%) 2 (4.2%) 3 (6.3%) 3 (6.3%) 23 (47.9%) 16 (33.3%)
total 124 5 (4.0%) 11 (8.9%) 19 (15.3%) 17 (13.8%) 51 (41.1%) 21 (16.9%)

*Fisher’s exact was applied between null and in-frame (p=0.261); Additionally, mutations (including null and in-frame) were compared with negative testing. Chi-Square test was applied between the intraocular tumor (including staging A, B, C, D, E) and extra-ocular tumor (χ2=14.9696, p=0.000):

He, Mol Vis 2014; 20:545-552. http://www.molvis.org/molvis/v20/545

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