Figure 3. Adrenomedullin_22–52 inhibited HREC migration induced by high glucose. HRECs were analyzed for the ability to migrate into a wound area using a scratch wound assay. A: After HRECs were wounded using a 200 μl yellow micropipette tip, they were incubated with serum-free media containing high glucose with or without adrenomedullin_22–52 for 24 h. The re-endothelialized monolayer area was photographed. A magnification of × 200 was used to image the re-endothelialized monolayer area. B: The quantitative data of the migration distance were from three independent experiments. All values represent Mean±SD (n=3). * p<0.05 versus the 30 mM group. # p<0.05 versus the 5 mM group.