Figure 3. STAT3 is activated at P18 in the rat 50/10 oxygen-induced retinopathy model (ROP model). (A) p-STAT3 and total STAT3 in the retinas from postnatal day 18 (P18) pups raised in room air (RA) and ROP model were measured by western blots; (B) STAT3 activity determined by the ratio of pSTAT3 to total STAT3 is increased in the ROP model (**p<0.01 versus standard deviation [SD], RA, two-way ANOVA).