Figure 4. The coat color phenotype correlates with the quantitative measurement of the Arf ^−/− lineage contribution to chimera. Charts display the average Arf ^−/− content in the tail-derived DNA (A), retinal pigment epithelium (RPE) (B), and cornea (C) in chimeric animals with light, mixed, and dark coats as indicated; error bars indicate standard deviation. The non-parametric trend test was used to account for the trend in color, and showed a significant correlation of coat color with the tail-derived DNA (p = 0.001) and RPE (p = 0.011), but not with the cornea (p = 0.155).