Table 4 of
Yang, Mol Vis 2014; 20:200-214. Table 4 of
Yang, Mol Vis 2014; 20:200-214.
Table 4. Genotype frequencies of polymorphisms in the studied groups
| Gene | SNP | Sample size | genotype | DR | DWR | OR (CI) | p-value |
|---|---|---|---|---|---|---|---|
| KDR | rs2071559 | 492 | TT | 84(39.3) | 141(50.7) | 0.034 | |
| CT | 95(44.4) | 103(37.1) | 1.73 (1,2.98) | ||||
| CC | 35(16.4) | 34(12.2) | 1.57 (1.05,2.28) | ||||
| rs1870377 | 490 | TT | 53(24.8) | 78(28.3) | 0.6 | ||
| TA | 113(52.8) | 134(48.6) | 1.24 (0.81,1.91) | ||||
| AA | 48(22.4) | 64(23.2) | 1.1 (0.66,1.84) | ||||
| rs1870378 | 471 | GG | 54(26.9) | 80(29.6) | 0.8 | ||
| GA | 97(48.3) | 126(46.7) | 1.14 (0.74,1.76) | ||||
| AA | 50(24.9) | 64(23.7) | 1.16 (0.7,1.92) | ||||
| rs13109660 | 490 | GG | 102(47.9) | 127(45.8) | 0.9 | ||
| GA | 93(43.7) | 125(45.1) | 0.93 (0.64,1.35) | ||||
| AA | 18(8.5) | 25(9) | 0.9 (0.46,1.73) | ||||
| VEGF | rs699947 | 495 | CC | 105(48.6) | 162(58.1) | <0.001 | |
| CA | 79(36.6) | 104(37.3) | 1.17 (0.8,1.72) | ||||
| AA | 32(18.4) | 13(4.7) | 3.80 (1.91,7.57) | ||||
| rs833061 | 491 | TT | 104(49.1) | 158(56.6) | 0.001 | ||
| CT | 78(36.8) | 108(38.7) | 1.1 (0.75,1.61) | ||||
| CC | 30(14.2) | 13(4.7) | 3.6 (1.79,7.22) | ||||
| rs13207351 | 491 | GG | 105(48.8) | 158(57.2) | <0.001 | ||
| GA | 78(36.3) | 105(38) | 1.12 (0.76,1.64) | ||||
| AA | 32(14.9) | 13(4.7) | 3.7 (1.86,7.39) | ||||
| rs2146323 | 490 | CC | 112(52.3) | 167(60.5) | 0.006 | ||
| CA | 72(33.6) | 93(33.7) | 1.15 (0.78,1.7) | ||||
| AA | 30(14) | 16(5.8) | 2.8 (1.46,5.37) | ||||
| rs3025021 | 491 | TT | 5(2.4) | 9(3.2) | 0.21 | ||
| CT | 48(22.6) | 81(29) | 1.07 (0.34,3.37) | ||||
| CC | 159(75) | 189(67.7) | 1.51 (0.5,4.61) | ||||
| rs833069 | 497 | GG | 40(18.6) | 58(20.6) | 0.82 | ||
| GA | 105(48.8) | 138(51.8) | 1.1 (0.69,1.78) | ||||
| AA | 70(18.6) | 86(30.5) | 1.18 (0.71,1.97) | ||||
| rs2010963 | 495 | GG | 70(32.6) | 84(30) | 0.47 | ||
| GC | 111(51.6) | 140(50) | 0.95 (0.64,1.42) | ||||
| CC | 34(15.8) | 56(20) | 0.73 (0.43,1.24) | ||||
| rs3025039 | 498 | CC | 137(63.7) | 198(70.0) | 0.15 | ||
| CT | 69(32.1) | 47(28.3) | 2.6 (0.85,7.93) | ||||
| TT | 9(4.2) | 5(1.8) | 1.25 (0.85,1.84) | ||||
| ICAM-1 | rs5498 | 492 | AA | 92(42.8) | 138(49.8) | 0.078 | |
| GA | 100(46.5) | 123(44.4) | 1.22 (0.84,1.77) | ||||
| GG | 23(10.7) | 16(5.8) | 2.16 (1.08,4.30) | ||||
| EPO | rs507392 | 496 | TT | 141(65.3) | 181(64.6) | 0.68 | |
| CT | 65(30.1) | 81(28.9) | 1.03 (0.69,1.53) | ||||
| CC | 10(4.6) | 18(6.4) | 0.71 (0.32,1.59) | ||||
| rs551238 | 494 | AA | 141(65.3) | 182(65.5) | |||
| CA | 65(30.1) | 79(28.4) | 1.06 (0.72,1.58) | 0.74 | |||
| CC | 10(4.6) | 17(6.1) | 0.76 (0.34,1.71) | ||||
| rs1617640 | 491 | TT | 146(69.2) | 182(65) | |||
| GT | 55(26.1) | 82(29.3) | 0.84 (0.56,1.25) | 0.61 | |||
| GG | 10(4.7) | 16(5.7) | 0.78 (0.34,1.77) | ||||
| AKR1B1 | 759853 | 471 | GG | 145(70.7) | 167(62.8) | ||
| GA | 54(26.3) | 91(34.2) | 0.68 (0.46,1.02) | 0.18 | |||
| AA | 6(2.9) | 8(3.0) | 0.86 (0.29,2.55) | ||||
| ACE | 1800764 | 494 | TT | 88(40.9) | 98(35.1) | 0.31 | |
| CT | 99(46.0) | 134(48) | 0.83 (0.56,1.23) | ||||
| CC | 28(13) | 47(16.8) | 0.65 (0.38,1.14) | ||||
| rs9896208 | 496 | CC | 79(36.6) | 84(30) | 0.056 | ||
| TC | 97(44.9) | 156(55.7) | 0.66 (0.44,0.98) | ||||
| TT | 40(18.5) | 40(14.3) | 1.06 (0.62,1.82) | ||||
| PKC-β | 3,900,007 | 496 | AA | 69(31.9) | 99(35.4) | 0.36 | |
| GA | 111(51.4) | 126(45) | 1.26 (0.85,1.88) | ||||
| GG | 36(16.7) | 55(19.6) | 0.94 (0.56,1.58) | ||||
| 2575390 | 499 | CC | 193(89.4) | 251(88.7) | 0.95 | ||
| CG | 22(10.2) | 31(11.0) | 0.92 (0.52,1.64) | ||||
| GG | 1(0.5) | 1(0.4) | 1.3 (0.08,20.92) | ||||
| 3760106 | 492 | GG | 190(89.2) | 248(88.9) | 0.97 | ||
| GA | 22(10.3) | 30(10.8) | 1.31 (0.08,21) | ||||
| AA | 1(0.5) | 1(0.4) | 0.96 (0.54,1.71) | ||||