Figure 7. Detection of VEGF levels in HLE-B3-cells treated with XAV939. Cells were incubated in triplicate using three independent cell populations with 3 ml of serum-free media containing 1 µm XAV939 for 3 h in hypoxia. The asterisk (*) indicates a statistically significant decrease in the levels of VEGF (p<0.05) in cells treated with XAV939 as compared to the control cells at the end of 3 h of incubation in atmospheric oxygen.