Figure 10. Effect of XAV939 on α-SMA and fibronectin expression in HLE-B3 cells. The experiment was repeated three times using independent cell populations. The normalized lysates were analyzed for levels of α-SMA and fibronectin using ImageJ analysis. The asterisk (*) indicates a significant decrease in the expression of both α-SMA and fibronectin in the XAV939-treated samples as compared to the corresponding control samples treated with DMSO (p<0.05).