Figure 4. Family 581 haplotypes from SNP chip data (black lettering) and Sanger sequencing using gene-specific primers (red lettering). The affected haplotype is boxed. The symbol definitions are the same for Figure 1. The inferred haplotype is shown for V:3 (not genotyped). More than 100 markers were analyzed to generate these haplotypes. The chromosome 22 positions are reported using hg19/GRCh37 coordinates.