Figure 7. Daily systemic valproic acid (VPA; P17–P28, later treatment) increased the rate of photoreceptor loss in Pde6b^rd10/rd10 mice. Retina sections are shown from two different treated and two different control littermates at age P28. White arrows indicate the outer nuclear layer and regions shown at higher magnification (inserts). Daily injections (IP) of 350 mg/kg VPA from age P17 to P28. A: Central retina; B: middle retina; C: peripheral retina (sections are paraffin, hematoxylin and eosin stained).