Figure 5. Delayed-type hypersensitivity responses to S-antigen peptide. The delayed-type hypersensitivity (DTH) responses to the S-antigen (S-Ag) peptide in rats with experimental autoimmune uveoretinitis (EAU) treated with vehicle (n=10), low-dose fenofibrate (FF(20)), and high-dose fenofibrate (FF(100)) were 4.32±0.92, 3.69±0.82, and 2.15±0.49 mm, respectively. Rats treated with a high dose of fenofibrate exhibited significant inhibition of ear swelling 48 h after S-Ag peptide challenge compared with the vehicle- or low-dose fenofibrate-treated rats. The results are presented as the mean ± standard deviation (SD). *p<0.0001 versus vehicle-treated group, **p=0.0003 versus low-dose fenofibrate-treated group.