Figure 3. Dp71 is the major dystrophin isoform expressed in the crystalline lens. Levels of the expression of DMD gene products and AQP0 in lenses and retinas from wt and KO-Dp71 mice were analyzed by immunoblotting. Actin levels were used as a loading control. As in the retina, Dp71 is the main DMD gene product expressed in the lens. We also detected Dp427, Dp260, and Dp140 in the retinas, as well as Dp260 and Dp140 in the lenses from both strains.