Table 1 of
Smith, Mol Vis 2014; 20:1328-1356. Table 1 of
Smith, Mol Vis 2014; 20:1328-1356.
Table 1. Superarray qPCR screening targets and fold change between WT and α7 nAChR KO mice.
| Target | Description | Fold change |
|---|---|---|
| Accn1 | amiloride-sensitive cation channel 1, neuronal, hair cell | −1.03 |
| Accn2 | neuronal asic 1a | −1.17 |
| Accn3 | amiloride-sensitive cation channel 3, dorsal root ganglion | 1.06 |
| Cacna1a | calcium channel, voltage-dependent, P/Q type, α 1A, brain | 1.17 |
| Cacna1b | calcium channel, voltage-dependent, N type, α 1B, brain sensory | 1.00 |
| Cacna1g | calcium channel, voltage-dependent, T type cardiac and brain | −1.03 |
| Cacna1h | calcium channel, voltage-dependent, T type, α 1H, neuronal | −1.08 |
| Cacnb3 | calcium channel, voltage-dependent, β 3 subunit, olfactory bulb | −1.03 |
| Cacnb4 | voltage gated calcium channel lymphocytes, cardiac and absence seizures | −1.07 |
| Cftr | CFTR | 1.15 |
| Chat | choline acetyltransferase (Chat) | 1.09 |
| Chrm1 | cholinergic receptor, muscarinic 1 brain | -1.78* |
| Chrm2 | cholinergic receptor, muscarinic 2, cardiac | 1.18 |
| Chrm3 | cholinergic receptor, muscarinic 3, cardiac | 1.17 |
| Chrm4 | cholinergic receptor, muscarinic 4 brain | 1.12 |
| Chrm5 | cholinergic receptor, muscarinic 5 brain | −1.16 |
| Chrna1 | cholinergic receptor, nicotinic, α polypeptide 1 | −1.08 |
| Chrna2 | cholinergic receptor, nicotinic, α polypeptide 2 | 1.06 |
| Chrna3 | cholinergic receptor, nicotinic, α polypeptide 3 | −1.15 |
| Chrna4 | cholinergic receptor, nicotinic, α polypeptide 4, brain | −1.12 |
| Chrna5 | cholinergic receptor, nicotinic, α polypeptide 5 | -1.50* |
| Chrna6 | cholinergic receptor, nicotinic, α polypeptide 6 | −1.07 |
| Chrna7 | cholinergic receptor, nicotinic, α polypeptide 7 | -103.61*** |
| Chrna9 | cholinergic receptor, nicotinic, α polypeptide 9 | 1.72 |
| Chrna10 | cholinergic receptor, nicotinic, α polypeptide 10 | 1.33 |
| Chrnb1 | cholinergic receptor, nicotinic, β polypeptide 1, motor neurons | 1.18 |
| Chrnb2 | cholinergic receptor, nicotinic, β polypeptide 2 | 1.00 |
| Chrnb4 | cholinergic receptor, nicotinic, β polypeptide 4 | −1.06 |
| Htr3a | 5HT 3a | −1.13 |
| Chrnb3 | cholinergic receptor, nicotinic, β polypeptide 3 | 1.05 |
| Clca1 | chloride channel calcium activated 1 (Clca1), brain | −1.03 |
| Clcn2 | chloride channel 2, astrocytes, salivary gland | 1.20 |
| Clcn4–2 | chloride channel 4–2 (Clcn4–2), taste bud, brain | 1.15 |
| Clcn6 | chloride channel 6, brain | −1.07 |
| Gabra1 | λ-aminobutyric acid (GABA-A) receptor, subunit α 1 | 1.02 |
| Gabra2 | λ-aminobutyric acid (GABA-A) receptor, subunit α 2 | −1.10 |
| Gabra3 | λ-aminobutyric acid (GABA-A) receptor, subunit α 3 | −1.07 |
| Gabra4 | λ-aminobutyric acid (GABA-A) receptor, subunit α 4 | 1.15 |
| Gabra5 | λ-aminobutyric acid (GABA-A) receptor, subunit α 5 | 1.08 |
| Gabra6 | λ-aminobutyric acid (GABA-A) receptor, subunit α 6 | NA |
| Gabrb2 | λ-aminobutyric acid (GABA-A) receptor, subunit β 2 | 1.19* |
| Gabrb3 | λ-aminobutyric acid (GABA-A) receptor, subunit β 3 | 1.07 |
| Gabrd | λ-aminobutyric acid (GABA-A) receptor, subunit Δ | 1.03 |
| Gabrg2 | λ-aminobutyric acid (GABA-A) receptor, subunit λ 2 | 1.16 |
| Gabrp | λ-aminobutyric acid (GABA-A) receptor, π | −1.36 |
| Gabrq | λ-aminobutyric acid (GABA-A) receptor, subunit θ | −1.04 |
| Gabrr1 | λ-aminobutyric acid (GABA-C) receptor, subunit ρ 1 | −1.09 |
| Gabrr2 | λ-aminobutyric acid (GABA-A) receptor, subunit ρ 2 | 1.10 |
| Gabrr3 | λ-aminobutyric acid (GABA-A) receptor, subunit ρ 3 | 1.07 |
| Glra1 | glycine receptor α 1 | 1.09 |
| Glra2 | glycine receptor, α 2 subunit | 1.15 |
| Glra3 | glycine receptor, α 3 subunit | −1.20 |
| Glra4 | glycine receptor, α 4 | 1.01 |
| Glrb | glycine receptor, β subunit | −1.06 |
| Kcna2 | potassium voltage-gated channel, shaker-related, brain and spinal cord | 1.02 |
| Kcna6 | potassium voltage-gated channel, shaker-related, brain | −1.04 |
| Kcnc4 | potassium voltage gated channel, Shaw-related, neurotransmitter release | 1.06 |
| Kcnd1 | potassium voltage-gated channel, Shal, brain | −1.01 |
| Kcnh2 | potassium voltage-gated channel, subfamily H, brain, ear | −1.03 |
| Kcnj3 | potassium inwardly-rectifying channel, subfamily J, spinal interneurons | −1.09 |
| Kcnj4 | frontal cortex pyramidal neurons HCN, Kir2, and Kleak | -1.98* |
| Kcnj6 | potassium inwardly-rectifying channel, subfamily J, brain | 1.01 |
| Kcnn2 | potassium channel calcium-activated, subfamily N, synaptic plasticity | 1.21 |
| Kcnn3 | potassium intermediate/small conductance, Ca2+ activated, N type, brain | −1.28 |
| Kcnq2 | potassium voltage-gated channel, subfamily Q, hippocampus | 1.02 |
| Kcnq3 | potassium voltage-gated channel, subfamily Q, member 3, brain | 1.18 |
| Ryr3 | ryanodine receptor 3 | 1.22 |
| Scn1a | sodium channel, voltage-gated, type I, brain | 1.08 |
| Scn1b | sodium channel, voltage-gated, type I, β brain & cardiac | −1.12 |
| Scn5a | sodium channel, voltage-gated, type V, cardiac and brain | 1.29 |
| Scn7a | sodium channel, voltage-gated, type VII, sodium concentration sensor, taste | 1.07 |
| Slc5a7 | solute carrier family 5 (high affinity choline transporter), member 7 | −1.01 |
| Gria1 | AMPA 1 cerebllum | 1.03 |
| Gria2 | AMPA 2 synaptic | 1.14 |
| Gria3 | AMPA 3, als | 1.14 |
| Gria4 | AMPA 4 alcohol use | 1.19 |
| Grik1 | kainate 1 presynaptic | 1.06 |
| Grik2 | kainate 2 mossy fiber, synaptic plasticity | 1.11 |
| Grik5 | kainate 5 mossy fiber | 1.15 |
| Grin1 | NMDA NR1 brain | −1.05 |
| Grin2a | NMDA NR2a brain | −1.08 |
| Grin2b | NMDA NR2b brain | 1.17 |
| Grin2c | NMDA NR2c brain | 1.13 |
| Grin2d | NMDA NR2d brain | −1.16 |
| Grin3a | NMDA NR3a | 1.04 |
| Grin3b | NMDA3b motor neurons | 1.09 |
| Vdac1 | voltage-dependent anion channel 1 | 1.02 |
| Hsp90ab1 | heat shock protein 90 α (cytosolic), class B member 1 | 1.16 |
| Actb | actin, β | Avg Ct=22.3 |
| Gapdh | glyceraldehyde-3-phosphate dehydrogenase | Avg Ct=23.4 |
| Gusb | glucuronidase, β | Avg Ct=32.6 |
| Hprt1 | hypoxanthine guanine phosphoribosyl transferase 1 | Avg Ct=23.8 |
| MGDC | mouse genomic DNA contamination | No amp |
| RTC | reverse transcription control | No amp |
| PPC | positive PCR control | Avg Ct=18 |