Figure 1. Pedigree of a family with retinitis pigmentosa associated with a c.2543del mutation in RPGR ORF15. Clinically examined individuals are indicated with an asterisk. All family members with bone spicules indicative of
typical retinitis pigmentosa (RP) are shown shaded in black as affected. Individuals with myopia (−3.0 to −15.0 diopter sphere)
but no pigmentary retinopathy are shown shaded in gray. Individuals III:4, III:9, IV:2, IV:4, and IV:11 were positive for
the disease-causing mutation, whereas III:3 and IV:12 were negative. For individuals II:5, III:1, III:6, III:7, III:11, IV:1,
IV:3, IV:6, IV:8, IV:15, and V:1, no DNA was available for laboratory investigation.