Figure 5. Western blot analysis of S100A4 and OPN in rat retinas. Significant increases in the expressions of S100A4 and both intact and cleaved OPN in the retinas of diabetic rats (D) compared to those of the nondiabetic control rats (C). Each experiment was repeated 3X with fresh samples (n = 8). *The difference between the two means was statistically significant at the 5% level.