Figure 3. Results of direct bisulfite sequencing for two differentially methylated CpG sites of DUSP22 in ocular adnexal extranodal marginal zone B-cell lymphoma. A: The first CpG site, target ID cg15383120, promoter, CpG island. B: The second CpG site, target ID cg11235426, nonpromoter, CpG island. Each row represents a bacterial clone with a circle
symbolizing a CpG site. Methylated and unmethylated CpG sites are indicated by black and white circles, respectively. Mutated
sites are indicated by gray circles. Correlation analysis between the Infinium methylation chip assay and bisulfite sequencing
revealed that only the second CpG site showed significant correlation between the two methods.