Table 2 of Liao, Mol Vis 2014; 20:1025-1036.


Table 2. Results of meta-analysis for APOE gene polymorphism and risk for primary open-angle glaucoma.

Category ε2/ε2 versus ε3/ε3OR (95%CI)P value (Model*) ε2/ε3 versus ε3/ε3OR (95%CI)P value (Model*) ε2/ε4 versus ε3/ε3OR (95%CI)P value (Model*) ε3/ε4 versus ε3/ε3OR (95%CI)P value (Model*) ε4/ε4 versus ε3/ε3OR (95%CI)P value (Model*) ε2allele versus ε3 alleleOR (95%CI)P value (Model*) ε4 allele versus ε3 alleleOR (95%CI)P value (Model*) Reference
POAG: 1.03(0.40–2.69)
0.95F 0.87(0.62–1.24)
0.44R 1.03(0.67–1.57)
0.90F 1.01(0.72–1.41)
0.97R 2.09(1.12–3.88)
0.02F 0.99(0.83–1.18)
0.91F 1.07(0.81–1.42)
0.65R 26–37
Subgroup:
Asian 2.10(0.30–14.63)
0.45F 0.74(0.42–1.29)
0.29R 1.09(0.58–2.05)
0.79F 1.00(0.54–1.87)
0.99R 3.55(1.06–11.87)
0.04F 0.96(0.75–1.23)
0.77F 1.06(0.61–1.82)
0.84R 26–30
Caucasian 0.79(0.26–2.44)
0.68F 1.00(0.72–1.39)
0.99F 0.87(0.30–2.57)
0.80R 1.02(0.77–1.34)
0.90F 1.65(0.79–3.45)
0.19F 1.02(0.80–1.30)
0.90F 1.10(0.89–1.35)
0.37F 31–37
HTG 1.14(0.28–4.59)
0.85F 0.91(0.52–1.57)
0.73R 0.69(0.20–2.36)
0.55R 0.93(0.69–1.25)
0.63F 1.19(0.39–3.61)
0.76F 0.87(0.56–1.36)
0.53R 0.96(0.66–1.41)
0.84R 27, 28, 30, 31, 35
NTG 1.53(0.42–5.59)
0.52F 0.80(0.48–1.33)
0.38F 1.86(0.87–4.01)
0.11F 1.37(0.67–2.81)
0.40R 1.66(0.65–4.26)
0.29F 1.06(0.73–1.55)
0.77F 1.30(0.97–1.76)
0.08F 30, 35, 36