Table 2 of
Liao, Mol Vis 2014; 20:1025-1036. Table 2 of
Liao, Mol Vis 2014; 20:1025-1036.
Table 2. Results of meta-analysis for APOE gene polymorphism and risk for primary open-angle glaucoma.
| Category | ε2/ε2 versus ε3/ε3 OR (95%CI) P value (Model*) | ε2/ε3 versus ε3/ε3 OR (95%CI) P value (Model*) | ε2/ε4 versus ε3/ε3 OR (95%CI) P value (Model*) | ε3/ε4 versus ε3/ε3 OR (95%CI) P value (Model*) | ε4/ε4 versus ε3/ε3 OR (95%CI) P value (Model*) | ε2allele versus ε3 allele OR (95%CI) P value (Model*) | ε4 allele versus ε3 allele OR (95%CI) P value (Model*) | Reference |
|---|---|---|---|---|---|---|---|---|
| POAG: | 1.03(0.40–2.69) 0.95F | 0.87(0.62–1.24) 0.44R | 1.03(0.67–1.57) 0.90F | 1.01(0.72–1.41) 0.97R | 2.09(1.12–3.88) 0.02F | 0.99(0.83–1.18) 0.91F | 1.07(0.81–1.42) 0.65R | 26–37 |
| Subgroup: | ||||||||
| Asian | 2.10(0.30–14.63) 0.45F | 0.74(0.42–1.29) 0.29R | 1.09(0.58–2.05) 0.79F | 1.00(0.54–1.87) 0.99R | 3.55(1.06–11.87) 0.04F | 0.96(0.75–1.23) 0.77F | 1.06(0.61–1.82) 0.84R | 26–30 |
| Caucasian | 0.79(0.26–2.44) 0.68F | 1.00(0.72–1.39) 0.99F | 0.87(0.30–2.57) 0.80R | 1.02(0.77–1.34) 0.90F | 1.65(0.79–3.45) 0.19F | 1.02(0.80–1.30) 0.90F | 1.10(0.89–1.35) 0.37F | 31–37 |
| HTG | 1.14(0.28–4.59) 0.85F | 0.91(0.52–1.57) 0.73R | 0.69(0.20–2.36) 0.55R | 0.93(0.69–1.25) 0.63F | 1.19(0.39–3.61) 0.76F | 0.87(0.56–1.36) 0.53R | 0.96(0.66–1.41) 0.84R | 27, 28, 30, 31, 35 |
| NTG | 1.53(0.42–5.59) 0.52F | 0.80(0.48–1.33) 0.38F | 1.86(0.87–4.01) 0.11F | 1.37(0.67–2.81) 0.40R | 1.66(0.65–4.26) 0.29F | 1.06(0.73–1.55) 0.77F | 1.30(0.97–1.76) 0.08F | 30, 35, 36 |