Figure 7. Effects of sCD44 on outflow rate in perfusion cultured anterior segments. After stabilization of the flow rate, time 0 represents the start of the treatment. Normalized flow rate is the percent change of the flow rate of the treated time points to average flow rate of the pre-treated time points. Porcine anterior segments were perfused at constant pressure with 1 ng/ml sCD44, 1 ng/ml heat-inactivated sCD44 (HIsCD44), 20 ng/ml BSA, or Dulbecco’s Modified Eagle’s Medium. Time points are the mean ± SEM and the number of experiments are shown in the insert. sCD44 versus Dulbecco’s Modified Eagle’s Medium (DMEM). The statistical comparisons are: sCD44 versus Dulbecco's Modified Eagle's Medium (DMEM), *p<0.05, **p<0.01; sCD44 versus HIsCD44, † p<0.05, †† p<0.01.